G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium.

Scaife, Robin M

G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium. [electronic resource] - Molecular cancer therapeutics Oct 2004 - 1229-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1535-7163


Animals
Antioxidants--metabolism
Apoptosis
Aurora Kinase A
Aurora Kinases
Blotting, Western
Cell Cycle
Cell Cycle Proteins
Cell Line
Cell Line, Tumor
Cell Proliferation
Centrosome--metabolism
Chromatids--metabolism
Cyclin B--biosynthesis
Cyclin B1
DNA--metabolism
Down-Regulation
Enzyme Inhibitors--pharmacology
Flavoproteins--antagonists & inhibitors
Flow Cytometry
G2 Phase
Humans
MAP Kinase Signaling System
Mice
Microscopy, Confocal
Microscopy, Fluorescence
Microscopy, Phase-Contrast
Mitosis
NIH 3T3 Cells
Onium Compounds--pharmacology
Paclitaxel--pharmacology
Phosphorylation
Protein Kinases--metabolism
Protein Serine-Threonine Kinases
Rats
Reactive Oxygen Species--metabolism
Spindle Apparatus--metabolism
Threonine--chemistry
Time Factors
Xenopus Proteins