Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway.

Schnurr, Max

Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. [electronic resource] - Blood Feb 2005 - 1582-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2004-05-1718 doi


Adenosine Triphosphate--pharmacology
Animals
Cells, Cultured
Cyclic AMP--physiology
Dendritic Cells--immunology
Down-Regulation--immunology
Escherichia coli--immunology
Extracellular Space--metabolism
Humans
Immunologic Memory
Interferon-gamma--antagonists & inhibitors
Interleukin-12--antagonists & inhibitors
Interleukin-23
Interleukin-23 Subunit p19
Interleukins--biosynthesis
Mice
Monocytes--immunology
Orthomyxoviridae--immunology
Receptors, Purinergic P2--physiology
Resting Phase, Cell Cycle--immunology
Signal Transduction--immunology
T-Lymphocyte Subsets--cytology
Up-Regulation--immunology