Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells.

Fauconnier, Jérémy

Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells. [electronic resource] - American journal of physiology. Heart and circulatory physiology Feb 2005 - H778-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0363-6135

10.1152/ajpheart.00542.2004 doi


Action Potentials--drug effects
Animals
Arrhythmias, Cardiac--chemically induced
Calcium--metabolism
Calcium Channels, L-Type--physiology
Electrocardiography
Extracellular Space--metabolism
Heart Rate
Immunosuppressive Agents--pharmacology
In Vitro Techniques
Long QT Syndrome--chemically induced
Myocytes, Cardiac--drug effects
Pacemaker, Artificial
Patch-Clamp Techniques
Potassium Channels, Inwardly Rectifying--physiology
Rats
Rats, Inbred WKY
Sodium--metabolism
Tacrolimus--pharmacology