"Teaching old drugs to kill new bugs": structure-based discovery of anti-SARS drugs.

Rajnarayanan, Rajendram V

"Teaching old drugs to kill new bugs": structure-based discovery of anti-SARS drugs. [electronic resource] - Biochemical and biophysical research communications Aug 2004 - 370-8 p. digital

Publication Type: Journal Article

0006-291X

10.1016/j.bbrc.2004.06.155 doi


Antiviral Agents--chemistry
Binding Sites
Computational Biology
Coronavirus 3C Proteases
Crystallography, X-Ray
Cyclization
Cysteine Endopeptidases
Drug Design
Drug Evaluation, Preclinical
Endopeptidases--chemistry
Ligands
Models, Molecular
Molecular Structure
Protein Structure, Tertiary
Severe acute respiratory syndrome-related coronavirus--drug effects
Structure-Activity Relationship
Urea--chemistry
Viral Proteins--antagonists & inhibitors