TEL2, an ETS factor expressed in human leukemia, regulates monocytic differentiation of U937 Cells and blocks the inhibitory effect of TEL1 on ras-induced cellular transformation.

Kawagoe, Hiroyuki

TEL2, an ETS factor expressed in human leukemia, regulates monocytic differentiation of U937 Cells and blocks the inhibitory effect of TEL1 on ras-induced cellular transformation. [electronic resource] - Cancer research Sep 2004 - 6091-100 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0008-5472

10.1158/0008-5472.CAN-04-0839 doi


Animals
Calcitriol--antagonists & inhibitors
Cell Differentiation--drug effects
Cell Transformation, Neoplastic--pathology
DNA-Binding Proteins--antagonists & inhibitors
Gene Expression Regulation, Leukemic
Hematopoietic Stem Cells--cytology
Humans
Leukemia, Myeloid--genetics
Mice
Monocytes--cytology
Mutation
NIH 3T3 Cells
Proto-Oncogene Proteins c-ets
RNA, Messenger--biosynthesis
Repressor Proteins--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factors--biosynthesis
Transcriptional Activation
Transfection
U937 Cells
Up-Regulation
ras Proteins--genetics
ETS Translocation Variant 6 Protein