EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways.

Qiu, Q

EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways. [electronic resource] - Reproduction (Cambridge, England) Sep 2004 - 355-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-1626

10.1530/rep.1.00234 doi


Blotting, Western--methods
Butadienes--pharmacology
Cell Line
Chromones--pharmacology
Enzyme Activation--drug effects
Epidermal Growth Factor--pharmacology
Female
Humans
MAP Kinase Signaling System--drug effects
Matrix Metalloproteinase 9--analysis
Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors
Morpholines--pharmacology
Nitriles--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Phosphoinositide-3 Kinase Inhibitors
Pregnancy
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins--antagonists & inhibitors
Proto-Oncogene Proteins c-akt
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Tissue Inhibitor of Metalloproteinase-1--analysis
Trophoblasts--metabolism