PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.

Schabbauer, Gernot

PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Oct 2004 - 1963-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1524-4636

10.1161/01.ATV.0000143096.15099.ce doi


Androstadienes--pharmacology
Animals
Blood Coagulation--physiology
Chemokines--metabolism
Chromones--pharmacology
Cytokines--metabolism
Disease Models, Animal
Endothelial Cells--drug effects
Endothelium, Vascular--drug effects
Endotoxemia--metabolism
Humans
Inflammation--metabolism
Kidney--pathology
Lipopolysaccharides--immunology
Liver--pathology
Macrophage Activation--physiology
Mice
Mice, Inbred C57BL
Monocytes--physiology
Morpholines--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Phosphoinositide-3 Kinase Inhibitors
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins--antagonists & inhibitors
Proto-Oncogene Proteins c-akt
Signal Transduction--physiology
Wortmannin