Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2.

Liang, Min

Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2. [electronic resource] - Molecular and cellular biology Sep 2004 - 7524-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.24.17.7524-7537.2004 doi


Amino Acid Motifs
Animals
Cell Line
Cysteine Endopeptidases--metabolism
DNA-Binding Proteins--genetics
Humans
JNK Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinases--metabolism
Multienzyme Complexes--metabolism
Neoplasms--genetics
Proteasome Endopeptidase Complex
Protein Binding
Protein Processing, Post-Translational
RNA Interference
Recombinant Fusion Proteins--genetics
S-Phase Kinase-Associated Proteins--genetics
Signal Transduction--physiology
Smad4 Protein
Trans-Activators--genetics
Ubiquitin--metabolism
Ubiquitin-Protein Ligases--genetics
p38 Mitogen-Activated Protein Kinases