Sensitization to the lysosomal cell death pathway upon immortalization and transformation.

Fehrenbacher, Nicole

Sensitization to the lysosomal cell death pathway upon immortalization and transformation. [electronic resource] - Cancer research Aug 2004 - 5301-10 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472

10.1158/0008-5472.CAN-04-1427 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Caspase 3
Caspase Inhibitors
Caspases--genetics
Cathepsin B--antagonists & inhibitors
Cathepsin D--antagonists & inhibitors
Cathepsin L
Cathepsins--antagonists & inhibitors
Cell Transformation, Neoplastic
Cysteine Endopeptidases
Cytochromes c--metabolism
Drug Resistance, Neoplasm
Embryo, Mammalian--cytology
Enzyme Activation
Enzyme Inhibitors--pharmacology
Fibroblasts--cytology
Genes, ras--physiology
Genes, src--physiology
Lysosomes--enzymology
Mice
Mice, Inbred C57BL
Mice, Knockout
NIH 3T3 Cells
RNA Interference
Signal Transduction
Transfection
Tumor Necrosis Factor-alpha--pharmacology