Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells.

Menendez, Javier A

Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells. [electronic resource] - Oncology reports Aug 2004 - 411-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1021-335X


Antifungal Agents--pharmacology
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis
Cell Line, Tumor
Cerulenin--pharmacology
Coloring Agents--pharmacology
DNA--metabolism
Dose-Response Relationship, Drug
Drug Synergism
Fatty Acid Synthases--antagonists & inhibitors
Humans
Inhibitory Concentration 50
Tetrazolium Salts--pharmacology
Thiazoles--pharmacology
Time Factors
Vinblastine--analogs & derivatives
Vinorelbine