The rate of cocaine administration alters gene regulation and behavioral plasticity: implications for addiction.

Samaha, Anne-Noël

The rate of cocaine administration alters gene regulation and behavioral plasticity: implications for addiction. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jul 2004 - 6362-70 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

1529-2401

10.1523/JNEUROSCI.1205-04.2004 doi


Animals
Behavior, Animal--drug effects
Brain--drug effects
Cocaine--administration & dosage
Cocaine-Related Disorders--etiology
Cytoskeletal Proteins
Dopamine--metabolism
Dopamine Uptake Inhibitors--administration & dosage
Drug Administration Schedule
Frontal Lobe--drug effects
Gene Expression Regulation--drug effects
Genes, Immediate-Early--drug effects
Genes, fos--drug effects
Immediate-Early Proteins--biosynthesis
In Situ Hybridization
Infusions, Intravenous
Limbic System--drug effects
Locomotion--drug effects
Male
Neostriatum--drug effects
Nerve Tissue Proteins--biosynthesis
Nucleus Accumbens--drug effects
Prefrontal Cortex--drug effects
Proto-Oncogene Proteins c-fos--biosynthesis
Rats
Rats, Sprague-Dawley