Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli.

Cheng, Ting-Jen

Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli. [electronic resource] - Antimicrobial agents and chemotherapy Jul 2004 - 2437-47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0066-4804

10.1128/AAC.48.7.2437-2447.2004 doi


Amides--metabolism
Blotting, Western
Cost-Benefit Analysis
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical--economics
Escherichia coli--drug effects
HIV Protease Inhibitors--pharmacology
HIV-1--drug effects
Humans
Mutagenesis
Plasmids--genetics
Reproducibility of Results
Reverse Transcriptase Polymerase Chain Reaction
beta-Galactosidase--metabolism