FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway.

Man, Kwan

FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway. [electronic resource] - Annals of surgery Jul 2004 - 159-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0003-4932

10.1097/01.sla.0000129673.13552.c0 doi


Animals
Apoptosis
Chemokine CXCL2
Chemokines--metabolism
Chemokines, CXC--metabolism
DNA-Binding Proteins--metabolism
Down-Regulation--drug effects
Early Growth Response Protein 1
Endothelin-1--metabolism
Gene Expression
Graft Survival--drug effects
Heat-Shock Proteins--metabolism
Heme Oxygenase (Decyclizing)
Hypertension, Portal--etiology
Immediate-Early Proteins--metabolism
Intercellular Signaling Peptides and Proteins--metabolism
Liver--blood supply
Liver Transplantation--adverse effects
Male
Nitric Oxide Donors--administration & dosage
Nitro Compounds--administration & dosage
Oxygenases
Preoperative Care
Proteins--metabolism
RNA, Messenger--metabolism
Rats
Rats, Inbred Lew
Reperfusion
Signal Transduction--drug effects
Tissue Donors
Tissue and Organ Harvesting
Transcription Factors--metabolism
Zinc Fingers