The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities.

Yakunin, Alexander F

The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities. [electronic resource] - The Journal of biological chemistry Aug 2004 - 36819-27 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M405120200 doi


Adenosine Monophosphate--metabolism
Amino Acid Sequence
Aspartic Acid--chemistry
Calcium--chemistry
Chromatography, Thin Layer
Cloning, Molecular
Conserved Sequence
Cyclic AMP--metabolism
Cyclic CMP--metabolism
Cyclic GMP--metabolism
Dose-Response Relationship, Drug
Escherichia coli--enzymology
Histidine--chemistry
Hydrolysis
Ions
Kinetics
Magnesium--chemistry
Manganese--chemistry
Models, Chemical
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Nickel--chemistry
Nucleotidases--metabolism
Phosphoric Diester Hydrolases--metabolism
Protein Structure, Tertiary
RNA Nucleotidyltransferases--chemistry
Substrate Specificity