Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain.

de Mol, Nico J

Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain. [electronic resource] - Biochimica et biophysica acta Jul 2004 - 53-64 p. digital

Publication Type: Journal Article

0006-3002

10.1016/j.bbapap.2004.03.016 doi


Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport--metabolism
Amino Acid Sequence
Animals
Deuterium Exchange Measurement
GRB2 Adaptor Protein
Kinetics
Ligands
Mice
Peptide Fragments--chemistry
Phosphotyrosine--metabolism
Protein Binding
Proteins--chemistry
Shc Signaling Adaptor Proteins
Spectrometry, Mass, Electrospray Ionization
Src Homology 2 Domain-Containing, Transforming Protein 1
Surface Plasmon Resonance
src Homology Domains