An important functional role of the N terminus domain of type VI adenylyl cyclase in Galphai-mediated inhibition.

Kao, Yu-Ya

An important functional role of the N terminus domain of type VI adenylyl cyclase in Galphai-mediated inhibition. [electronic resource] - The Journal of biological chemistry Aug 2004 - 34440-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M401952200 doi


Adenylyl Cyclases--metabolism
Animals
Blotting, Western
CHO Cells
Catalytic Domain
Cell Line
Cell Membrane--metabolism
Cricetinae
Dose-Response Relationship, Drug
Electrophoresis, Polyacrylamide Gel
GTP-Binding Protein alpha Subunit, Gi2
GTP-Binding Protein alpha Subunits, Gi-Go--metabolism
Humans
Inhibitory Concentration 50
Leucine--chemistry
Models, Biological
Models, Molecular
Mutagenesis, Site-Directed
Mutation
Plasmids--metabolism
Polymerase Chain Reaction
Protein Binding
Protein Conformation
Protein Isoforms
Protein Structure, Secondary
Protein Structure, Tertiary
Proto-Oncogene Proteins--metabolism
Rats
Recombinant Proteins--chemistry
Transfection
Valine--chemistry