Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor.

Nordal, Robert A

Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2004 - 3342-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1078-0432

10.1158/1078-0432.CCR-03-0426 doi


Animals
Astrocytes--metabolism
Central Nervous System--radiation effects
DNA, Complementary--metabolism
DNA-Binding Proteins--metabolism
Dose-Response Relationship, Radiation
Female
Glial Fibrillary Acidic Protein--metabolism
Humans
Hypoxia
Hypoxia-Inducible Factor 1
Hypoxia-Inducible Factor 1, alpha Subunit
Immunohistochemistry
In Situ Hybridization
Mice
Mice, Transgenic
Microcirculation
Monosaccharide Transport Proteins--metabolism
Necrosis
Nuclear Proteins--metabolism
RNA--metabolism
Rats
Rats, Inbred F344
Spinal Cord--metabolism
Spinal Cord Injuries--pathology
Time Factors
Transcription Factors--metabolism
Up-Regulation
Vascular Endothelial Growth Factor A--metabolism