Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors.
O'Neill, David J
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors. [electronic resource] - Bioorganic & medicinal chemistry Jun 2004 - 3167-85 p. digital
Publication Type: Journal Article
0968-0896
10.1016/j.bmc.2004.04.010 doi
Animals
Aza Compounds--chemical synthesis
Cell Line
Drug Design
Enzyme Inhibitors--chemical synthesis
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Humans
Maleimides--chemical synthesis
Microsomes, Liver--drug effects
Molecular Structure
Rabbits
Substrate Specificity
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors. [electronic resource] - Bioorganic & medicinal chemistry Jun 2004 - 3167-85 p. digital
Publication Type: Journal Article
0968-0896
10.1016/j.bmc.2004.04.010 doi
Animals
Aza Compounds--chemical synthesis
Cell Line
Drug Design
Enzyme Inhibitors--chemical synthesis
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Humans
Maleimides--chemical synthesis
Microsomes, Liver--drug effects
Molecular Structure
Rabbits
Substrate Specificity