Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A.

Howard, E I

Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A. [electronic resource] - Proteins Jun 2004 - 792-804 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

1097-0134

10.1002/prot.20015 doi


Acetates--chemistry
Aldehyde Reductase--chemistry
Binding Sites
Crystallography, X-Ray
Drug Design
Electrons
Enzyme Inhibitors--chemistry
Hydrogen--chemistry
Models, Molecular
Molecular Structure
Protein Conformation
Solvents--chemistry
Thioamides
Thiocarbamates--chemistry