Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes.

Desai, Devashish

Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes. [electronic resource] - Biochemical and biophysical research communications Jun 2004 - 642-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-291X

10.1016/j.bbrc.2004.04.073 doi


Aged
Aged, 80 and over
Aspartic Acid Endopeptidases--antagonists & inhibitors
Astrocytes--drug effects
Butadienes--pharmacology
Cell Division--drug effects
Cell Hypoxia--physiology
Cell Line, Tumor
Cells, Cultured
Cycloheximide--pharmacology
Dactinomycin--pharmacology
Endothelin Receptor Antagonists
Endothelin-1--metabolism
Endothelin-Converting Enzymes
Enzyme Inhibitors--pharmacology
Glycopeptides--pharmacology
Humans
Metalloendopeptidases
Mitogen-Activated Protein Kinases--antagonists & inhibitors
Nitriles--pharmacology
Oligopeptides--pharmacology
Optic Disk--cytology
Protease Inhibitors--pharmacology
Tumor Necrosis Factor-alpha--pharmacology