Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo.

Sheline, Christian T

Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. [electronic resource] - Annals of neurology May 2004 - 645-53 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0364-5134

10.1002/ana.20047 doi


Adenosine Triphosphatases--biosynthesis
Animals
Cation Transport Proteins--biosynthesis
Cell Death--drug effects
Cells, Cultured
Copper--toxicity
Copper-Transporting ATPases
Enzyme Activation--drug effects
Enzyme Inhibitors--toxicity
Female
Hepatolenticular Degeneration--genetics
Ketoglutarate Dehydrogenase Complex--antagonists & inhibitors
Ketone Oxidoreductases--antagonists & inhibitors
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mitochondria--drug effects