A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease.

Vega, Sonia

A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease. [electronic resource] - Proteins May 2004 - 594-602 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1097-0134

10.1002/prot.20069 doi


Amides--chemistry
Binding Sites
Crystallography, X-Ray
Dipeptides--chemistry
Drug Resistance, Viral--genetics
HIV Protease--chemistry
HIV Protease Inhibitors--chemistry
HIV-1--drug effects
Models, Molecular
Mutation
Thermodynamics
Thiazoles--chemistry