Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element.

François, Mathias

Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element. [electronic resource] - The Journal of biological chemistry Jul 2004 - 28411-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M312708200 doi


Animals
Binding Sites
Blotting, Northern
Blotting, Western
Cartilage--metabolism
Cell Nucleus--metabolism
Cells, Cultured
Chondrocytes--metabolism
Cloning, Molecular
DNA, Complementary--metabolism
Dose-Response Relationship, Drug
Down-Regulation
Fibrinolytic Agents--pharmacology
Genes, Dominant
Humans
Immunohistochemistry
Interleukin-1--metabolism
Kinetics
Ligands
Luciferases--metabolism
Matrix Metalloproteinase 1--metabolism
Mutagenesis, Site-Directed
Mutation
NF-kappa B--metabolism
Promoter Regions, Genetic
Protein Binding
Proteoglycans--metabolism
RNA--metabolism
RNA, Messenger--metabolism
Rabbits
Receptors, Cytoplasmic and Nuclear--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Rosiglitazone
Sulfates--metabolism
Thiazolidinediones--pharmacology
Time Factors
Transcription Factor AP-1--metabolism
Transcription Factors--metabolism
Transcription, Genetic
Transfection