BACE (beta-secretase) modulates the processing of APLP2 in vivo.

Pastorino, L

BACE (beta-secretase) modulates the processing of APLP2 in vivo. [electronic resource] - Molecular and cellular neurosciences Apr 2004 - 642-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1044-7431

10.1016/j.mcn.2003.12.013 doi


Alzheimer Disease--enzymology
Amyloid Precursor Protein Secretases
Amyloid beta-Peptides--metabolism
Amyloid beta-Protein Precursor--genetics
Animals
Aspartic Acid Endopeptidases--deficiency
Brain--enzymology
Brain Chemistry--genetics
Cells, Cultured
Disease Models, Animal
Down-Regulation--genetics
Endopeptidases
Genes, Reporter--genetics
Genetic Vectors--genetics
Humans
Mice
Mice, Knockout
Mice, Transgenic
Nerve Tissue Proteins--genetics
Neurons--enzymology
Transfection
beta-Galactosidase--genetics