Quinoxaline 1,4-dioxides are novel angiogenesis inhibitors that potentiate antitumor effects of ionizing radiation.

Gali-Muhtasib, Hala

Quinoxaline 1,4-dioxides are novel angiogenesis inhibitors that potentiate antitumor effects of ionizing radiation. [electronic resource] - International journal of oncology May 2004 - 1121-31 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1019-6439


Adenocarcinoma--blood supply
Angiogenesis Inhibitors--therapeutic use
Animals
Blotting, Western
Carcinoma, Lewis Lung--blood supply
Cell Hypoxia--drug effects
Cell Survival--drug effects
Collagen--chemistry
Combined Modality Therapy
Drug Combinations
Female
Hypoxia-Inducible Factor 1, alpha Subunit
Laminin--chemistry
Mammary Neoplasms, Experimental--blood supply
Mice
Mice, Inbred C57BL
Necrosis
Neovascularization, Pathologic--prevention & control
Proteoglycans--chemistry
Quinoxalines--therapeutic use
Radiation Tolerance
Radiation, Ionizing
Radiation-Sensitizing Agents
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factors--genetics
Tumor Cells, Cultured
Tumor Stem Cell Assay
Vascular Endothelial Growth Factor A--genetics