Micromolar concentrations of sodium arsenite induce cyclooxygenase-2 expression and stimulate p42/44 mitogen-activated protein kinase phosphorylation in normal human epidermal keratinocytes.

Trouba, K J

Micromolar concentrations of sodium arsenite induce cyclooxygenase-2 expression and stimulate p42/44 mitogen-activated protein kinase phosphorylation in normal human epidermal keratinocytes. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Jun 2004 - 248-57 p. digital

Publication Type: Journal Article

1096-6080

10.1093/toxsci/kfh132 doi


Arsenites--toxicity
Blotting, Northern
Blotting, Western
Cells, Cultured
Cyclooxygenase 2
Dinoprostone--metabolism
Enzyme Inhibitors--pharmacology
Gene Expression Regulation, Enzymologic
Humans
Keratinocytes--drug effects
Membrane Proteins
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--antagonists & inhibitors
Phosphorylation
Prostaglandin-Endoperoxide Synthases--biosynthesis
RNA, Messenger--biosynthesis
Sodium Compounds--toxicity