Mechanisms responsible for the in vitro relaxation of a novel dibenzothiepine derivative (NSU-242) on tracheal and vascular smooth muscles.

Ozaki, Hiroshi

Mechanisms responsible for the in vitro relaxation of a novel dibenzothiepine derivative (NSU-242) on tracheal and vascular smooth muscles. [electronic resource] - European journal of pharmacology Mar 2004 - 191-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2999

10.1016/j.ejphar.2004.02.017 doi


Actin Cytoskeleton--metabolism
Actomyosin--pharmacology
Animals
Bronchoconstriction--drug effects
Carbachol--antagonists & inhibitors
Cyclic AMP--metabolism
Cyclic GMP--metabolism
Dibenzothiepins--pharmacology
Guinea Pigs
In Vitro Techniques
Muscarinic Agonists--pharmacology
Muscle Relaxation--drug effects
Muscle, Smooth--drug effects
Muscle, Smooth, Vascular--drug effects
Myosin Light Chains--metabolism
Phosphorylation
Potassium Chloride--antagonists & inhibitors
Swine
Trachea--drug effects