Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2.
Abu-Bakar, A'edah
Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2. [electronic resource] - Toxicology letters Mar 2004 - 199-210 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0378-4274
10.1016/j.toxlet.2003.10.029 doi
Acute Disease
Animals
Aryl Hydrocarbon Hydroxylases--biosynthesis
Blotting, Northern
Blotting, Western
Cadmium Poisoning--enzymology
Cytochrome P-450 CYP2A6
Cytochrome P450 Family 2
DNA-Binding Proteins--physiology
Dose-Response Relationship, Drug
Kidney--drug effects
Liver--drug effects
Male
Mice
Mice, Inbred DBA
Mice, Knockout
Microsomes--enzymology
Microsomes, Liver--enzymology
Mixed Function Oxygenases--biosynthesis
NF-E2-Related Factor 2
RNA, Messenger--biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Trans-Activators--physiology
Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2. [electronic resource] - Toxicology letters Mar 2004 - 199-210 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0378-4274
10.1016/j.toxlet.2003.10.029 doi
Acute Disease
Animals
Aryl Hydrocarbon Hydroxylases--biosynthesis
Blotting, Northern
Blotting, Western
Cadmium Poisoning--enzymology
Cytochrome P-450 CYP2A6
Cytochrome P450 Family 2
DNA-Binding Proteins--physiology
Dose-Response Relationship, Drug
Kidney--drug effects
Liver--drug effects
Male
Mice
Mice, Inbred DBA
Mice, Knockout
Microsomes--enzymology
Microsomes, Liver--enzymology
Mixed Function Oxygenases--biosynthesis
NF-E2-Related Factor 2
RNA, Messenger--biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Trans-Activators--physiology