Dissociation between biochemical and functional effects of the aldose reductase inhibitor, ponalrestat, on peripheral nerve in diabetic rats.

Cameron, N E

Dissociation between biochemical and functional effects of the aldose reductase inhibitor, ponalrestat, on peripheral nerve in diabetic rats. [electronic resource] - British journal of pharmacology Dec 1992 - 939-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1111/j.1476-5381.1992.tb13389.x doi


Aldehyde Reductase--antagonists & inhibitors
Animals
Blood Glucose--analysis
Body Weight--drug effects
Diabetic Neuropathies--physiopathology
Fructose--analysis
Hypoglycemic Agents--pharmacology
Hypoxia--physiopathology
Male
Neural Conduction--drug effects
Peripheral Nerves--drug effects
Phthalazines--pharmacology
Rats
Rats, Sprague-Dawley
Sciatic Nerve--chemistry
Sorbitol--analysis