Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.

Kang-Decker, Ningling

Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. [electronic resource] - Cancer cell Feb 2004 - 177-89 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

1535-6108

10.1016/s1535-6108(04)00022-4 doi


Animals
CREB-Binding Protein
Cell Cycle Proteins--metabolism
Cloning, Molecular
Cyclin E--metabolism
Cyclin-Dependent Kinase Inhibitor p27
DNA Damage--physiology
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Genes, myc--physiology
Genetic Predisposition to Disease
Lymphoma, T-Cell--genetics
Membrane Proteins--metabolism
Mice
Mice, Knockout
Microscopy, Fluorescence
Nuclear Proteins--genetics
Polycomb Repressive Complex 1
Proto-Oncogene Proteins--metabolism
Receptors, Notch
Repressor Proteins
S-Phase Kinase-Associated Proteins--metabolism
T-Lymphocytes--metabolism
Trans-Activators--genetics
Tumor Suppressor Protein p53--genetics
Tumor Suppressor Proteins--metabolism
Up-Regulation--physiology