A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells.

Kikuchi, Yasufumi

A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells. [electronic resource] - Biochemical and biophysical research communications Mar 2004 - 912-8 p. digital

Publication Type: Journal Article

0006-291X

10.1016/j.bbrc.2004.01.128 doi


Animals
Antibodies, Monoclonal--chemistry
Antigens, CD--immunology
Apoptosis--drug effects
Binding Sites
CD47 Antigen
CHO Cells
Carrier Proteins--immunology
Cell Line, Tumor
Cell Survival--drug effects
Cricetinae
Dimerization
Flow Cytometry--methods
Hemagglutination Tests
Humans
Immunoglobulin Fragments--genetics
Immunoglobulin G--blood
Immunoglobulin Variable Region--genetics
Leukemia L1210--immunology
Male
Mice
Mice, SCID
Multiple Myeloma--immunology
Neoplasm Transplantation--immunology
Recombinant Proteins--genetics