Enhanced rat Hershberger assay appears reliable for detection of not only (anti-)androgenic chemicals but also thyroid hormone modulators.

Yamada, Tomoya

Enhanced rat Hershberger assay appears reliable for detection of not only (anti-)androgenic chemicals but also thyroid hormone modulators. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology May 2004 - 64-74 p. digital

Publication Type: Comparative Study; Journal Article

1096-6080

10.1093/toxsci/kfh093 doi


Administration, Oral
Androgen Antagonists--chemistry
Animals
Antithyroid Agents--chemistry
Body Weight--drug effects
Castration--methods
Dichlorodiphenyl Dichloroethylene--administration & dosage
Drug Evaluation, Preclinical--methods
Eating--drug effects
Injections, Subcutaneous
Male
Organ Size--drug effects
Phenobarbital--administration & dosage
Propylthiouracil--administration & dosage
Rats
Rats, Inbred Strains
Reproducibility of Results
Testosterone Propionate--administration & dosage
Thyroid Gland--drug effects
Thyrotropin--blood
Thyroxine--blood
Triiodothyronine--blood