Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models.
Adikwu, Michael U
Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models. [electronic resource] - Biomaterials Jul 2004 - 3041-8 p. digital
Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
0142-9612
10.1016/j.biomaterials.2003.09.073 doi
Adhesiveness
Animals
Blood Glucose--analysis
Chemistry, Pharmaceutical--methods
Culture Techniques
Diabetes Mellitus, Experimental--blood
Drug Compounding--methods
Drug Delivery Systems--methods
Excipients--pharmacokinetics
Galactose--administration & dosage
Hypoglycemic Agents--administration & dosage
Intestinal Mucosa--drug effects
Male
Metformin--administration & dosage
Plant Gums
Rats
Rats, Wistar
Streptozocin
Tensile Strength--drug effects
Tissue Adhesives--pharmacokinetics
Treatment Outcome
Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models. [electronic resource] - Biomaterials Jul 2004 - 3041-8 p. digital
Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
0142-9612
10.1016/j.biomaterials.2003.09.073 doi
Adhesiveness
Animals
Blood Glucose--analysis
Chemistry, Pharmaceutical--methods
Culture Techniques
Diabetes Mellitus, Experimental--blood
Drug Compounding--methods
Drug Delivery Systems--methods
Excipients--pharmacokinetics
Galactose--administration & dosage
Hypoglycemic Agents--administration & dosage
Intestinal Mucosa--drug effects
Male
Metformin--administration & dosage
Plant Gums
Rats
Rats, Wistar
Streptozocin
Tensile Strength--drug effects
Tissue Adhesives--pharmacokinetics
Treatment Outcome