An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo.
Stallmach, A
An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo. [electronic resource] - Gut Mar 2004 - 339-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0017-5749
10.1136/gut.2003.020107 doi
Adult
Animals
Apoptosis--drug effects
Cell Division--drug effects
Cells, Cultured
Colitis--chemically induced
Crohn Disease--immunology
Disease Models, Animal
Dose-Response Relationship, Drug
Female
Humans
Immunoglobulin G--metabolism
Interferon-gamma--biosynthesis
Interleukin-12--metabolism
Interleukin-12 Subunit p40
Leukocytes, Mononuclear--drug effects
Male
Mice
Mice, Inbred BALB C
Middle Aged
Prospective Studies
Protein Subunits--metabolism
Receptors, Interleukin--metabolism
Receptors, Interleukin-12
Recombinant Fusion Proteins--metabolism
Trinitrobenzenesulfonic Acid
An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo. [electronic resource] - Gut Mar 2004 - 339-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0017-5749
10.1136/gut.2003.020107 doi
Adult
Animals
Apoptosis--drug effects
Cell Division--drug effects
Cells, Cultured
Colitis--chemically induced
Crohn Disease--immunology
Disease Models, Animal
Dose-Response Relationship, Drug
Female
Humans
Immunoglobulin G--metabolism
Interferon-gamma--biosynthesis
Interleukin-12--metabolism
Interleukin-12 Subunit p40
Leukocytes, Mononuclear--drug effects
Male
Mice
Mice, Inbred BALB C
Middle Aged
Prospective Studies
Protein Subunits--metabolism
Receptors, Interleukin--metabolism
Receptors, Interleukin-12
Recombinant Fusion Proteins--metabolism
Trinitrobenzenesulfonic Acid