Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele.
Karray, Saoussen
Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 2004 - 2118-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-1767
10.4049/jimmunol.172.4.2118 doi
Alleles
Animals
Autoantibodies--blood
CD3 Complex--biosynthesis
CD4 Antigens--metabolism
CD8 Antigens--metabolism
Cell Movement--genetics
Crosses, Genetic
Fas Ligand Protein
Female
Gene Deletion
Gene Silencing--immunology
Glomerulonephritis--genetics
Hypergammaglobulinemia--genetics
Leukocyte Common Antigens--biosynthesis
Ligands
Liver--immunology
Lymphoproliferative Disorders--genetics
Male
Membrane Glycoproteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Mutant Strains
Mice, Transgenic
Salivary Glands--immunology
T-Lymphocyte Subsets--immunology
fas Receptor--metabolism
Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 2004 - 2118-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-1767
10.4049/jimmunol.172.4.2118 doi
Alleles
Animals
Autoantibodies--blood
CD3 Complex--biosynthesis
CD4 Antigens--metabolism
CD8 Antigens--metabolism
Cell Movement--genetics
Crosses, Genetic
Fas Ligand Protein
Female
Gene Deletion
Gene Silencing--immunology
Glomerulonephritis--genetics
Hypergammaglobulinemia--genetics
Leukocyte Common Antigens--biosynthesis
Ligands
Liver--immunology
Lymphoproliferative Disorders--genetics
Male
Membrane Glycoproteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Mutant Strains
Mice, Transgenic
Salivary Glands--immunology
T-Lymphocyte Subsets--immunology
fas Receptor--metabolism