Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats.

Brochot, Céline

Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats. [electronic resource] - Journal of pharmaceutical sciences Mar 2004 - 553-62 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0022-3549

10.1002/jps.10574 doi


Animals
Drug Interactions
Male
Norfloxacin--pharmacokinetics
Pefloxacin--pharmacokinetics
Rats
Rats, Sprague-Dawley
Seizures--chemically induced
Theophylline--pharmacokinetics