Cleavage of poly(A)-binding protein by poliovirus 3C protease inhibits host cell translation: a novel mechanism for host translation shutoff.

Kuyumcu-Martinez, N Muge

Cleavage of poly(A)-binding protein by poliovirus 3C protease inhibits host cell translation: a novel mechanism for host translation shutoff. [electronic resource] - Molecular and cellular biology Feb 2004 - 1779-90 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.24.4.1779-1790.2004 doi


3C Viral Proteases
Catalysis
Cell Extracts
Cysteine Endopeptidases--metabolism
Eukaryotic Initiation Factor-4G
HeLa Cells
Humans
Kinetics
Peptide Fragments--metabolism
Peptide Initiation Factors--metabolism
Poliovirus--enzymology
Poly(A)-Binding Proteins--chemistry
Protein Biosynthesis
RNA Stability
RNA, Messenger--genetics
Viral Proteins--metabolism