Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats.

Collier, Timothy J

Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats. [electronic resource] - Neurobiology of aging Feb 2004 - 209-21 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0197-4580

10.1016/s0197-4580(03)00042-3 doi


Adrenergic alpha-Agonists--pharmacokinetics
Adrenergic alpha-Antagonists--pharmacokinetics
Adrenergic beta-Antagonists--pharmacokinetics
Aging--physiology
Animals
Autoradiography
Avoidance Learning
Behavior, Animal
Brain Chemistry
Cerebral Cortex--anatomy & histology
Chromatography, High Pressure Liquid
Clonidine--pharmacokinetics
Hippocampus--metabolism
Iodocyanopindolol--pharmacokinetics
Male
Maze Learning--physiology
Memory Disorders--physiopathology
Methoxyhydroxyphenylglycol--metabolism
Norepinephrine--metabolism
Phobic Disorders--physiopathology
Prazosin--pharmacokinetics
Radioligand Assay--methods
Rats
Rats, Inbred F344
Space Perception--drug effects