Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.

Xavier, Sandhya

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. [electronic resource] - The Journal of biological chemistry Apr 2004 - 15167-76 p. digital

Publication Type: Journal Article

0021-9258

10.1074/jbc.M309798200 doi


Animals
Blotting, Northern
Blotting, Western
COS Cells
Carcinoma, Squamous Cell--drug therapy
Cell Line
Cell Line, Tumor
Cells, Cultured
DNA-Binding Proteins--metabolism
Dose-Response Relationship, Drug
Down-Regulation
Fibrosis--metabolism
Gene Deletion
Genes, Reporter
Humans
Immunoblotting
MAP Kinase Signaling System
Mice
Mice, Inbred C3H
Microscopy, Confocal
Microscopy, Fluorescence
Piperidines
Plasmids--metabolism
Protein Synthesis Inhibitors--therapeutic use
Quinazolines--therapeutic use
Quinazolinones
Radiation Pneumonitis--drug therapy
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Smad3 Protein
Time Factors
Trans-Activators--metabolism
Transforming Growth Factor beta--metabolism
Transforming Growth Factor beta1