Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity.

Suen, Ka-Chun

Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity. [electronic resource] - Journal of neurochemistry Dec 2003 - 1413-26 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0022-3042

10.1111/j.1471-4159.2003.02259.x doi


Amyloid beta-Peptides--toxicity
Analysis of Variance
Animals
Blotting, Western
Boron Compounds--pharmacology
Calcium--metabolism
Carrier Proteins--metabolism
Caspase 3
Caspases--metabolism
Cell Death--drug effects
Cells, Cultured
Cerebral Cortex--cytology
Dose-Response Relationship, Drug
Drug Interactions
Embryo, Mammalian
Endoplasmic Reticulum--drug effects
Endoplasmic Reticulum Chaperone BiP
Enzyme Inhibitors--pharmacology
Heat-Shock Proteins
Immunosuppressive Agents--pharmacology
Indoles--metabolism
Intracellular Space--drug effects
L-Lactate Dehydrogenase--metabolism
Macrocyclic Compounds
Molecular Chaperones--metabolism
Neurons--drug effects
Oxazoles--pharmacology
Peptide Fragments--toxicity
Rats
Rats, Sprague-Dawley
Tacrolimus--pharmacology
Time Factors