Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity.

Zhou, Wenbo

Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity. [electronic resource] - The Journal of biological chemistry Mar 2004 - 10128-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M307563200 doi


Adenoviridae--genetics
Animals
Apoptosis
Blotting, Western
Cell Line
Cell Survival
Cloning, Molecular
Cysteine--chemistry
Detergents--pharmacology
Dimerization
Electrophoresis, Polyacrylamide Gel
Humans
Immunohistochemistry
Magnetic Resonance Spectroscopy
Mice
Microscopy, Fluorescence
Mutagenesis, Site-Directed
Mutation
Nerve Tissue Proteins--chemistry
Neurons--metabolism
Nitrogen--chemistry
Octoxynol--pharmacology
Oxidative Stress
Oxygen--metabolism
Phenylalanine--chemistry
Plasmids--chemistry
Protein Binding
Proteins--chemistry
Rats
Recombinant Proteins--chemistry
Synucleins
Time Factors
Transfection
Tyrosine--chemistry
alpha-Synuclein
beta-Synuclein