Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression.

Lange, Patricia A

Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression. [electronic resource] - Biochemical and biophysical research communications Jan 2004 - 546-51 p. digital

Publication Type: Journal Article

0006-291X

10.1016/j.bbrc.2003.12.003 doi


Active Transport, Cell Nucleus
Animals
Blotting, Western
Cell Division
Cell Transformation, Neoplastic
Collagenases--metabolism
DNA--metabolism
DNA-Binding Proteins--biosynthesis
Down-Regulation
Fibrosis
Hepatocytes--metabolism
Male
Mice
Mice, Inbred BALB C
Protein Binding
Signal Transduction
Smad Proteins
Smad2 Protein
Smad3 Protein
Smad4 Protein
Thymidine--chemistry
Time Factors
Trans-Activators--biosynthesis
Transforming Growth Factor beta--metabolism