Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug.

Ask, K

Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug. [electronic resource] - Chemical research in toxicology Dec 2003 - 1547-54 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0893-228X

10.1021/tx0340910 doi


Amines--chemistry
Anaerobiosis
Androgen Antagonists--adverse effects
Animals
Cattle
Electron Spin Resonance Spectroscopy
Free Radicals--chemistry
Imidazoles--adverse effects
Imidazolidines
Mice
NADP--metabolism
Nitric Oxide Synthase--genetics
Nitric Oxide Synthase Type I
Nitric Oxide Synthase Type II
Nitric Oxide Synthase Type III
Oxidation-Reduction
Rats
Recombinant Proteins--genetics
Time Factors