Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.

Steckelbroeck, Stephan

Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action. [electronic resource] - The Journal of biological chemistry Mar 2004 - 10784-95 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M313308200 doi


17-Hydroxysteroid Dehydrogenases--chemistry
Androgens--metabolism
Catalysis
Cell Line
Cytosol--enzymology
DNA, Complementary--metabolism
Flufenamic Acid--pharmacology
GABA Antagonists--chemistry
Humans
Kinetics
Ligands
Magnetic Resonance Spectroscopy
Models, Biological
Models, Molecular
NADP--chemistry
Polymerase Chain Reaction
Protein Isoforms
RNA, Messenger--metabolism
Recombinant Proteins--chemistry
Software
Steroids--metabolism
Time Factors