The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling.

Reinoso-Martín, Cristina

The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. [electronic resource] - Eukaryotic cell Dec 2003 - 1200-10 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1535-9778

10.1128/EC.2.6.1200-1210.2003 doi


Antifungal Agents--pharmacology
Caspofungin
Cell Extracts
Cell Survival--drug effects
Cells, Cultured
DNA-Binding Proteins--genetics
Down-Regulation
Drug Tolerance--genetics
Echinocandins
Enzyme Activation--drug effects
Fungal Proteins--genetics
Gene Expression--drug effects
Genes, Fungal--drug effects
Kinetics
Lipopeptides
MAP Kinase Signaling System--drug effects
Mitogen-Activated Protein Kinases--genetics
Models, Biological
Oligonucleotide Array Sequence Analysis
Peptides--pharmacology
Peptides, Cyclic
Phosphorylation
Protein Kinase C--genetics
RNA, Messenger--metabolism
Repressor Proteins
Saccharomyces cerevisiae--enzymology
Saccharomyces cerevisiae Proteins--genetics
Signal Transduction