FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.

Beggs, Hilary E

FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. [electronic resource] - Neuron Oct 2003 - 501-14 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0896-6273

10.1016/s0896-6273(03)00666-4 doi


Animals
Astrocytes--metabolism
Bacterial Proteins--metabolism
Basement Membrane--metabolism
Blotting, Western
Calbindin 2
Calbindins
Carrier Proteins--metabolism
Cell Adhesion Molecules, Neuronal--metabolism
Cells, Cultured
Cerebral Cortex--abnormalities
Cytoskeletal Proteins--metabolism
DNA-Binding Proteins--metabolism
Disease Models, Animal
Dura Mater
Dystroglycans
Embryo, Mammalian
Extracellular Matrix Proteins--metabolism
Fibroblasts--metabolism
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Glial Fibrillary Acidic Protein--metabolism
Heterozygote
Homeodomain Proteins--metabolism
Immunohistochemistry
Infections
Intracellular Signaling Peptides and Proteins
Lamins--metabolism
Membrane Glycoproteins--metabolism
Mice
Mice, Knockout
Microscopy, Electron
Microtubule-Associated Proteins--metabolism
Muscular Dystrophies--congenital
Mutation
Nerve Tissue Proteins
Neurons--metabolism
Otx Transcription Factors
Phosphopyruvate Hydratase--metabolism
Phosphotyrosine--metabolism
Precipitin Tests
Protein-Tyrosine Kinases--deficiency
Reelin Protein
S100 Calcium Binding Protein G--metabolism
Serine Endopeptidases
Silver Staining
Staining and Labeling
Transcription Factors--metabolism
src-Family Kinases--metabolism