The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation.

Martin, Kathleen A

The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation. [electronic resource] - American journal of physiology. Cell physiology Mar 2004 - C507-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0363-6143

10.1152/ajpcell.00201.2003 doi


Animals
Aorta, Thoracic--cytology
Biomarkers
Cattle
Cell Cycle Proteins--metabolism
Cell Differentiation--drug effects
Cells, Cultured
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclins--metabolism
Endothelium, Vascular--cytology
Extracellular Matrix Proteins--metabolism
Immunosuppressive Agents--pharmacology
Muscle Contraction--drug effects
Muscle, Smooth, Vascular--cytology
Phenotype
Protein Kinases--metabolism
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
Signal Transduction--drug effects
Sirolimus--pharmacology
TOR Serine-Threonine Kinases
Tumor Suppressor Proteins--metabolism