The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells.

Sade, Hadassah

The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells. [electronic resource] - The Journal of biological chemistry Jan 2004 - 2937-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M309924200 doi


Apoptosis
Humans
Jurkat Cells
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)--metabolism
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-akt
Receptor, Notch1
Receptors, Cell Surface--metabolism
Signal Transduction
T-Lymphocytes--metabolism
Transcription Factors