Phase I study of detoxified Escherichia coli J5 lipopolysaccharide (J5dLPS)/group B meningococcal outer membrane protein (OMP) complex vaccine in human subjects.

Cross, Alan S

Phase I study of detoxified Escherichia coli J5 lipopolysaccharide (J5dLPS)/group B meningococcal outer membrane protein (OMP) complex vaccine in human subjects. [electronic resource] - Vaccine Nov 2003 - 4576-87 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0264-410X

10.1016/s0264-410x(03)00483-3 doi


Adolescent
Adult
Animals
Antibodies, Bacterial--analysis
Bacterial Outer Membrane Proteins--chemistry
Colony Count, Microbial
Cytokines--biosynthesis
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immune Sera--chemistry
Immunization, Secondary
Immunoglobulin A--biosynthesis
Immunoglobulin G--biosynthesis
Immunoglobulin M--biosynthesis
Lipopolysaccharides--chemistry
Male
Meningococcal Infections--microbiology
Meningococcal Vaccines--adverse effects
Middle Aged
Neisseria meningitidis--immunology
Rabbits
Rats
Rats, Sprague-Dawley
Vaccines, Conjugate--immunology