Mevinolin, a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase, suppresses enterocyte esterification of exogenous but not endogenous cholesterol.

Fellermann, K

Mevinolin, a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase, suppresses enterocyte esterification of exogenous but not endogenous cholesterol. [electronic resource] - Biochimica et biophysica acta Nov 1992 - 78-83 p. digital

Publication Type: Journal Article

0006-3002

10.1016/0005-2760(92)90078-a doi


Animals
Cell Line
Cholesterol--metabolism
Esterification
Humans
Hydroxymethylglutaryl CoA Reductases--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Intestinal Mucosa--metabolism
Intestines--cytology
Kinetics
Liposomes--metabolism
Lovastatin--pharmacology
Microsomes--metabolism
Rabbits
Sterol O-Acyltransferase--metabolism
Substrate Specificity